Projects

Research and engineering projects: connectome analysis, behavioural data pipelines, interactive web resources and reproducible scientific workflows.

A selection of my experimental and data science projects.

3D rendering of Drosophila optic lobe neurons.

Making sense of a fruit fly's neural wiring diagram

Visual system connectivity analysis and 3D visualisation of >50,000 neurons

The landing page of the Cell Type Explorer, the web resource we built, showing its counts of 11,751 neuron types, 164,838 neurons and 171,898,782 synapses above a quick-search box.

Connectome Cell Type Explorer

Python CLI to generate an interactive web resource from a connectome dataset

Illustration of a loose group of fruit flies walking in the same direction.

Experiments Data Analysis Pipeline

Characterisation of collective fruit fly behaviour to moving patterns

End-to-end pipeline for a high-throughput behavioural screen

Data visualisations of a single cell's response to flashes at different locations in space.

Pipeline for investigating neural responses to moving stimuli.

An adaptive, 2-step protocol that includes real-time neural response analysis

Schematic of the thesis: an owl striking at a fleeing mouse, the retina-to-superior-colliculus pathway in a mouse brain, a DNA helix, and a potassium channel.

Experiments Data Analysis Pipeline

Responses to visual threats in mouse models of autism

How genes linked to autism affect a circuit that drives innate responses to visual threats

Confocal micrographs of MADM mouse tissue in a control (left) and Lgl-/+ (right) mice.

Experiments Data Analysis

Investigating the role of Lgl1 function in cortical development

Single-cell genetic dissection using the mosaic analysis with double markers (MADM) technique

Confocal micrograph of stem cells transplanted into a mouse's gut.

Experiments Data Analysis

Characterising the gut nervous system in a disease mouse model

Cellular and molecular profiling in preparation for stem cell transplant therapies